6th The Awaji International Forum on Infection and Immunity  
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Hiroki YOSHIDA, M.D., Ph.D.

Department of Biomolecular Sciences,
Faculty of Medicine, Saga University
Selected references

1. Yoshida, H. et al. WSX-1 Is Required for the Initiation of Th1 Responses and Resistance to L. major Infection. Immunity 15, 569-78. (2001).
2. Takeda, A. et al. Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment. J Immunol 170, 4886-4890 (2003).
3. Hamano, S. et al. WSX-1 Is Required for Resistance to Trypanosoma cruzi Infection by Regulation of Proinflammatory Cytokine Production. Immunity 19, 657-667 (2003).
4. Villarino, A. et al. The IL-27R (WSX-1) Is Required to Suppress T Cell Hyperactivity during Infection. Immunity 19, 645-655 (2003).
5. Yamanaka, A. et al. Hyperproduction of Proinflammatory Cytokines by WSX-1-Deficient NKT Cells in Concanavalin A-Induced Hepatitis. J Immunol 172, 3590-3596 (2004).
6. Yoshida, H., Hamano, S. & Miyazaki, Y. Double identity of WSX-1 (IL-27R) as an initiator and attenuator of immune responses: Regulation by WSX-1 of pro-inflammatory cytokine production in the liver. Mucosal Immunology Update 12, 7-9 (2004).
7. Miyazaki, Y. et al. Exacerbation of Experimental Allergic Asthma by Augmented Th2 Responses in WSX-1-Deficient Mice. J Immunol 175, 2401-7 (2005).
8. Shimizu, S. et al. Membranous Glomerulonephritis Development with Th2-Type Immune Deviations in MRL/lpr Mice Deficient for IL-27 Receptor (WSX-1). J Immunol 175, 7185-92 (2005).
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