| |
| Koji Yasutomo, M.D., Ph.D.
Professor
Department of Immunology and Parasitology
Institute of Health Biosciences
The University of Tokushima Graduate School
3-18-15 Kuramoto, Tokushima 770-8503, Japan |
 |
Educations
| 1984-1990 |
School of Medicine, The University of Tokushima
(M.D., 1990) |
| 1993-1997 |
Graduate School of Medicine, The University of Tokushima
(Ph.D., 1997) |
| 1997-2000 |
Visiting Scientist, National Institute of Health, USA |
|
Positions
| 2001 |
Assistant Professor, Department of Pediatrics,
School of Medicine, The University of Tokushima |
| 2001 |
Professor, Department of Immunology and Parasitology, School
of Medicine, The University of Tokushima |
| 2004 |
Professor, Department of Immunology and Parasitology, Institute
of Health Biosciences, The University of Tokushima Graduate
School |
|
Selected Publications
| 1. |
Hisaeda H, Hamano S, Mitoma-Obata C, Tetsutani
K, Imai T, Waldmann H, Himeno K, Yasutomo K. Resistance to
GITR signaling in antigen specific CD4+CD25+ regulatory T
cells during Plasmodium yoelii infection. Eur J Immunol 35(12):3516-24,
2005. |
| 2. |
Maekawa Y, Yasutomo K. Antigen-driven T-cell repertoire
selection. Crit Rev Immunol. 25(1):59-74, 2005 |
| 3. |
Tsukumo SI and Yasutomo K. Notch governing mature T cell
differentiation. J Immunol 173(12):7109-13, 2004 |
| 4. |
Hayashi Y, Tsukumo SI, Kishihara K, Maekawa Y, Shiota H,
Yasutomo K. Antigen specific T-cell repertoire modification
of CD4+CD25+ regulatory T-cells. J Immunol 172(9):5240-8,
2004 |
| 5. |
Hisaeda H, Maekawa Y, Iwakawa D, Okada H, Himeno K, Kishihara
K, Tsukumo SI, Yasutomo K. Escape of malaria parasites from
host immunity requires CD4+CD25+ regulatory T-cells. Nature
Medicine 10(1):29-30, 2004 |
| 6. |
Maekawa Y, Tsukumo SI, Chiba S, Hirai H, Hayashi Y, Okada
H, Kishihara K, Yasutomo K. Delta1-Notch3 interactions bias
the functional differentiation of activated CD4+ T-cells.
Immunity 19(4):549-59, 2003 |
| 7. |
Yasutomo K, Horiuchi T, Kagami S, Tsukamoto S, Hashimura
C, Urushihara M, Kuroda Y. Mutation in DNASE I in people with
systemic lupus erythematosus. Nature Genet 28(4):313-314,
2001 |
| 8. |
Dorfman JR, Stefanova I, Yasutomo K, Germain RN. CD4+ T-cell
survival is not directly linked to self-MHC induced TCR signaling.
Nature Immunol 1(4):329-335, 2000 |
| 9. |
Yasutomo K, Doyle C, Miele L, Fuchs C, Germain RN. The
duration of antigen receptor signalling determines CD4+ versus
CD8+ T-cell lineage fate. Nature. 404(6777):506-10, 2000 |
| 10. |
Lu FW, Yasutomo K, Goodman GB, McHeyzer-Williams LJ, McHeyzer-Williams
MG, GermainRN, Ashwell JD. Thymocyte resistance to glucocorticoids
leads to antigen-specific unresponsiveness due to "holes"
in the T cell repertoire. Immunity. 12(2):183-92, 2000 |
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