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Kazuo Sugamura, M.D., Ph.D.
Professor
Department of Microbiology and Immunology
Tohoku University Graduate School of Medicine |
 |
Educations
| 1964-1970 |
Tohoku University School of Medicine, Sendai |
| 1970-1974 |
Graduate School of Tohoku University School of Medicine |
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Research and Professional Experience
| 1974-1976 |
Research Fellow, Institute of Cancer Research |
| 1976-1978 |
Research Fellow, Immunobiology Research Center, University
of Wisconsin, Madison |
| 1978-1980 |
Assistant Professor, Department of Microbiology, Kumamoto
University Medical School, Kumamoto |
| 1980-1986 |
Associate Professor, Institute for Virus Research, Kyoto
University, Kyoto |
| 1986-1997 |
Professor, Department of Microbiology and Immunology, Tohoku
University School of Medicine, Sendai |
| 1997-present |
Professor, Department of Microbiology and Immunology, Tohoku
University Graduate School of Medicine, Sendai |
| 2004-present |
Dean, Tohoku University Graduate School of Medicine, Sendai |
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Selected publications:
| 1. |
Sugamura, K. and Hinuma, Y.:
Human retrovirus in adult T-cell leukemia/lymphoma. Immunol.
Today, 6, 83-88, 1985. |
| 2. |
Takeshita, T., Asao, H., Ohtani, K., Ishii N., Kumaki, S.,
Tanaka, N., Munakata, H., Nakamura, M. and Sugamura,
K.: Cloning of the chain of the human IL-2 receptor.
Science, 257, 379-382, 1992. |
| 3. |
Kondo, M., Takeshita, T., Ishii, N., Nakamura, M., Watanabe,
S., Arai, K. and Sugamura, K.: Sharing of
the interleukin-2 (IL-2) receptor chain between receptors
for IL-2 and IL-4. Science, 262, 1874-1877,1993. |
| 4. |
Kondo, M., Takeshita, T., Ishii, N., Nakamura, M., Watanabe,
S., Arai, K. and Sugamura, K.: Sharing of
the interleukin-2 (IL-2) receptor chain between receptors
for IL-2 and IL-4. Science, 262, 1874-1877,1993. |
| 5. |
Sugamura, K., Asao, H., Kondo, M., Tanaka,
N., Ishii, N., Ohbo, K., Nakamura, M. and Takeshita, T.: The
interleukin 2 receptor g chain: its role in the multiple cytokine
receptor complexes and T cell development in XSCID. Annu.
Rev. Immunol., 14, 179-205, 1996. |
| 6. |
Takeshita, T., Arita, T., Higuchi, M., Asao, H., Endo, Y.,
Kuroda, H., Tanaka, N., Murata, K., Ishii, N. and Sugamura,
K.: STAM, signal transducing adaptor molecule, is
associated with Janus kinases and involved in signaling for
cell growth and c-myc induction. Immunity., 6, 449-457,
1997. |
| 7. |
Murata, K., Ishii, N., Takano, H., Miura, S., Ndhlovu, L.
C., Nose, M., Noda, T. and Sugamura, K.:
Impairment of antigen-presenting cell function in mice lacking
expression of OX40 ligand. J. Exp. Med., 191, 365-374,
2000 |
| 8. |
Sugamura, K., Ishii, N. and Weinberg, A.
D.: Therapeutic targeting of the effector T-cell co-stimulatory
molecule OX40. Nature Rev. Immunol., 4, 420-431,
2004. |
| 9. |
Kobayashi, H., Tanaka, N., Asao, H., Miura, S., Kyuuma,
M., Semura, K., Ishii, N. and Sugamura, K.:
Hrs, a mammalian master molecule in vesicular transport and
protein-sorting, suppresses the degradation of ESCRT proteins
STAM1 and STAM2. J. Biol. Chem., 180:10468-10477,
2005. |
| 10. |
Wang, X., Ria, M., Kelmenson, P. M., Eriksson, P., Higgins,
D. C., Sammegard, A., Petros, C., Olsson, P. G., Forsman-Semb,
K., Hamsten, A., Ishii, N., Sugamura, K.,
Lagercrantz, J. and Paigen, B.: Positional identification
of OX40 ligand as a gene that determines atherosclerosis susceptibility.
Nature Genetics,37:365-372, 2005. |
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