6th The Awaji International Forum on Infection and Immunity  
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Masayuki Miyasaka, M.D., Ph.D.

Professor
Laboratory of Immunodynamics,
Department of Microbiology and Immunology,
Osaka University Graduate School of Medicine,
2-2, Yamada-oka, Suita 565, Japan
EDUCATION

1967-1973 Faculty of Medicine, Kyoto University Medical School, Kyoto, Japan
Awarded the degree of M.D.
1977-1981 Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, Australia,
Awarded the degree of Ph.D. in Immunology
Research and Professional Experience:

2005- present Professor and Chairman, Laboratory of Immunodynamics, Department of Microbiology and Immunology, Osaka University Graduate School of Medicine
2001-2004 Professor and Chairman, Laboratory of Molecular & Cellular Recognition, Osaka University Graduate School of Medicine
1994-2001 Professor and Chairman, Department of Bioregulation, Biomedical Research Center, Osaka University Graduate School of Medicine
1987-1994 Head, Department of Immunology, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
1981-1986 Member, Basel Institute of Immunology, Basel, Switzerland
1977-1981 Ph.D. Scholar, Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, Australia
1974-1977 Assistant Professor, Department of Internal Medicine, Kanazawa Medical University, Uchinada, Ishikawa Prefecture, Japan
1973-1974 Intern, Kitano Hospital, Osaka, Japan
Recent publications

2006
1. Umemoto, E., Tanaka, T., Kanda, H., Jin, S., Tohya, K., Otani, K., Matsutani, T., Matsumoto, M., Ebisuno, Y., Jang, M.H., Fukuda, M., Hirata, T. & Miyasaka, M.: Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow. J. Exp. Med., in press.
2. *Uematsu, S., *Jang, M.H., Chevrier, N., Guo, Z., Kumagai, Y., Yamamoto, M., Kato, H., Sougawa, N., Matsui, H., Kuwata, H., Hemmi, H., Coban, C., Kawai, T., Ishii, K.J., Takeuchi, O., Miyasaka, M., Takeda, K. & Akira, S. (*equal contribution): TLR5 is highly expressed on intestinal CD11c+ lamina propria cells and utilized by S. typhimurium for systemic infection. Nat. Immunol., in press.
3. Jang, M.H., Seoh, J.-Y. & Miyasaka, M.: Cytokines, chemokines and their receptors: Targets for immunomodulation. J. Leuk. Biol., in press.
4. Sugahara, K.N, Hirata, T., Hayasaka, H., Stern, R., Murai, T. & Miyasaka, M.: Tumor cells enhance their own CD44 cleavage and motility by generating hyaluronan fragments. J. Biol. Chem., 281:5861-5868, 2006.
5. *Jang, M.H., *Sougawa, N., Tanaka, T., Hirata, T., Hiroi, T., Tohya, K., Guo, Z., Umemoto, E., Ebisuno, Y., Yang, B.-G., Seoh, J.-Y., Lipp, M., Kiyono, H. & Miyasaka, M. (*equal contribution): CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes. J. Immunol., 176:803-810, 2006.
   
2005
1. Matsumoto, M., Atarashi, K., Umemoto, E., Furukawa, Y., Shigeta, A., Miyasaka, M. & Hirata, T.: CD43 functions as a ligand for E-selectin on activated T cells. J. Immunol., 175:8042-8050, 2005.
2. Nakai, K., Tanaka, T., Murai, T., Ohguro, N., Tano, Y. & Miyasaka, M.: Invasive human pancreatic carcinoma cells adhere to endothelial tri-cellular corners and increase endothelial permeability. Cancer Sci., 96:766-773, 2005.
3. *Kanemitsu, N., *Ebisuno, Y., *Tanaka, T., Otani, K., Hayasaka, H., Kaisho, T., Akira, S., Katagiri, K., Kinashi, T., Fujita, N., Tsuruo, T. & Miyasaka, M. (*equal contribution): CXCL13 is an arrest chemokine for B cells in high endothelial venules. Blood, 106:2613-2618, 2005.
4. Tanaka, T., Bai, Z., Srinoulprasert, Y., Yang, B.-G., Hayasaka, H. & Miyasaka, M.: Review: Chemokines in tumor progression and metastasis. Cancer Sci., 96:317-322, 2005.
5. Atarashi, K., Hirata, T., Matsumoto, M., Kanemitsu, N. & Miyasaka, M.: Rolling of Th1 cells via P-selectin glycoprotein ligand-1 stimulates LFA-1-mediated cell binding to ICAM-1. J. Immunol., 174:1424-1432, 2005.
   
2004
1. Hirata, T., Furukawa, Y., Yang, B.-G., Hieshima, K., Fukuda, M., Kannagi, R., Yoshie, O. & Miyasaka, M.: Human PSGL-1 interacts with the skin-associated chemokine CCL27 via sulfated tyrosines at the PSGL-1 amino terminus. J. Biol. Chem., 279:51775-51782, 2004.
2. *Kanda, H., *Tanaka, T., Matsumoto, M., Umemoto, E., Ebisuno, Y., Kinoshita, M., Noda, M., Kannagi, R., Hirata, T., Murai, T., Fukuda, M. & Miyasaka, M. (*equal contribution): Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling. Int. Immunol., 16:1265-1274, 2004.
3. Miyasaka, M. & Tanaka, T.: Lymphocyte trafficking across high endothelial venules: Dogmas and enigmas. Nat. Rev. Immunol., 4:360-370, 2004.
 
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