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Masayuki Miyasaka, M.D., Ph.D.
Professor
Laboratory of Immunodynamics,
Department of Microbiology and Immunology,
Osaka University Graduate School of Medicine,
2-2, Yamada-oka, Suita 565, Japan |
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EDUCATION
| 1967-1973 |
Faculty of Medicine, Kyoto University Medical
School, Kyoto, Japan
Awarded the degree of M.D. |
| 1977-1981 |
Department of Immunology, John Curtin School of Medical
Research, Australian National University, Canberra, Australia,
Awarded the degree of Ph.D. in Immunology |
|
Research and Professional Experience:
| 2005- present |
Professor and Chairman, Laboratory of Immunodynamics,
Department of Microbiology and Immunology, Osaka University
Graduate School of Medicine |
| 2001-2004 |
Professor and Chairman, Laboratory of Molecular & Cellular
Recognition, Osaka University Graduate School of Medicine |
| 1994-2001 |
Professor and Chairman, Department of Bioregulation, Biomedical
Research Center, Osaka University Graduate School of Medicine |
| 1987-1994 |
Head, Department of Immunology, Tokyo Metropolitan Institute
of Medical Science, Tokyo, Japan |
| 1981-1986 |
Member, Basel Institute of Immunology, Basel, Switzerland |
| 1977-1981 |
Ph.D. Scholar, Department of Immunology, John Curtin School
of Medical Research, Australian National University, Canberra,
Australia |
| 1974-1977 |
Assistant Professor, Department of Internal Medicine, Kanazawa
Medical University, Uchinada, Ishikawa Prefecture, Japan |
| 1973-1974 |
Intern, Kitano Hospital, Osaka, Japan |
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Recent publications
| 2006 |
| 1. |
Umemoto, E., Tanaka, T., Kanda, H., Jin, S.,
Tohya, K., Otani, K., Matsutani, T., Matsumoto, M., Ebisuno,
Y., Jang, M.H., Fukuda, M., Hirata, T. & Miyasaka,
M.: Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent
lymphocyte rolling and promotes lymphocyte adhesion under
flow. J. Exp. Med., in press. |
| 2. |
*Uematsu, S., *Jang, M.H., Chevrier, N., Guo, Z., Kumagai,
Y., Yamamoto, M., Kato, H., Sougawa, N., Matsui, H., Kuwata,
H., Hemmi, H., Coban, C., Kawai, T., Ishii, K.J., Takeuchi,
O., Miyasaka, M., Takeda, K. & Akira,
S. (*equal contribution): TLR5 is highly expressed on intestinal
CD11c+ lamina propria cells and utilized by S. typhimurium
for systemic infection. Nat. Immunol., in press. |
| 3. |
Jang, M.H., Seoh, J.-Y. & Miyasaka, M.:
Cytokines, chemokines and their receptors: Targets for immunomodulation.
J. Leuk. Biol., in press. |
| 4. |
Sugahara, K.N, Hirata, T., Hayasaka, H., Stern, R., Murai,
T. & Miyasaka, M.: Tumor cells enhance
their own CD44 cleavage and motility by generating hyaluronan
fragments. J. Biol. Chem., 281:5861-5868, 2006. |
| 5. |
*Jang, M.H., *Sougawa, N., Tanaka, T., Hirata, T., Hiroi,
T., Tohya, K., Guo, Z., Umemoto, E., Ebisuno, Y., Yang, B.-G.,
Seoh, J.-Y., Lipp, M., Kiyono, H. & Miyasaka,
M. (*equal contribution): CCR7 is critically important
for migration of dendritic cells in intestinal lamina propria
to mesenteric lymph nodes. J. Immunol., 176:803-810,
2006. |
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| 2005 |
| 1. |
Matsumoto, M., Atarashi, K., Umemoto, E., Furukawa, Y.,
Shigeta, A., Miyasaka, M. & Hirata, T.:
CD43 functions as a ligand for E-selectin on activated T cells.
J. Immunol., 175:8042-8050, 2005. |
| 2. |
Nakai, K., Tanaka, T., Murai, T., Ohguro, N., Tano, Y. &
Miyasaka, M.: Invasive human pancreatic carcinoma
cells adhere to endothelial tri-cellular corners and increase
endothelial permeability. Cancer Sci., 96:766-773,
2005. |
| 3. |
*Kanemitsu, N., *Ebisuno, Y., *Tanaka, T., Otani, K., Hayasaka,
H., Kaisho, T., Akira, S., Katagiri, K., Kinashi, T., Fujita,
N., Tsuruo, T. & Miyasaka, M. (*equal
contribution): CXCL13 is an arrest chemokine for B cells in
high endothelial venules. Blood, 106:2613-2618, 2005. |
| 4. |
Tanaka, T., Bai, Z., Srinoulprasert, Y., Yang, B.-G., Hayasaka,
H. & Miyasaka, M.: Review: Chemokines
in tumor progression and metastasis. Cancer Sci.,
96:317-322, 2005. |
| 5. |
Atarashi, K., Hirata, T., Matsumoto, M., Kanemitsu, N. &
Miyasaka, M.: Rolling of Th1 cells via P-selectin
glycoprotein ligand-1 stimulates LFA-1-mediated cell binding
to ICAM-1. J. Immunol., 174:1424-1432, 2005. |
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| 2004 |
| 1. |
Hirata, T., Furukawa, Y., Yang, B.-G., Hieshima, K., Fukuda,
M., Kannagi, R., Yoshie, O. & Miyasaka, M.:
Human PSGL-1 interacts with the skin-associated chemokine
CCL27 via sulfated tyrosines at the PSGL-1 amino terminus.
J. Biol. Chem., 279:51775-51782, 2004. |
| 2. |
*Kanda, H., *Tanaka, T., Matsumoto, M., Umemoto, E., Ebisuno,
Y., Kinoshita, M., Noda, M., Kannagi, R., Hirata, T., Murai,
T., Fukuda, M. & Miyasaka, M. (*equal
contribution): Endomucin, a sialomucin expressed in high endothelial
venules, supports L-selectin-mediated rolling. Int. Immunol.,
16:1265-1274, 2004. |
| 3. |
Miyasaka, M. & Tanaka, T.: Lymphocyte
trafficking across high endothelial venules: Dogmas and enigmas.
Nat. Rev. Immunol., 4:360-370, 2004. |
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