|Kensuke Miyake, M.D., Ph.D.
||Graduated from Okayama University Medical School
||Finished the doctor course (Dr. Toshiyuki Hamaoka) at Osaka
University Medical School, receiving the degree of the Doctor
of Medical Science.
||Research associate in the Immunobiology and
cancer program, Oklahoma Medical Research foundation
(Dr. Paul W. Kincade)
||Assistant professor in the Department of Immunology, Saga
|| Associate professor in the Department of Immunology, Saga
||Professor, Division of Infectious Genetics, Department of
Microbiology and Immunology, The Institute of Medical Science,
The University of Tokyo
Y. Yamashita, M. Ogata, T. Sudo, and M. Kimoto. 1995. RP105,
a novel B cell surface molecule implicated in B cell activation,
is a member of the leucine-rich repeat protein family. J.
Immunol. 154: 3333-3340.
||Miyake, K., R. Shimazu, J. Kondo, T. Niki,
S. Akashi, H. Ogata, Y. Yamashita, Y. Miura, and M. Kimoto.
1998. Mouse MD-1, a molecule that is physically associated
with RP105 and positively regulates its expression. J.
Immunol. 161: 1348-1353.
||Shimazu, R., S. Akashi, H. Ogata, Y. Nagai, K. Fukudome,
K. Miyake, and M. Kimoto. 1999. MD-2, a molecule that confers
lipopolysaccharide responsiveness on Toll-like receptor 4.
J. Exp. Med. 189: 1777-1782.
||Ogata, H., I. Su, K. Miyake, Y. Nagai, S. Akashi, I. Mecklenbräuker,
K. Rajewsky, M. Kimoto, and A. Tarakhovsky. 2000. The Toll-like
Receptor Protein RP105 Regulates Lipopolysaccharide Signaling
in B Cells. J. Exp. Med. 192: 23-30.
||Nagai, Y., S. Akashi, M. Nagafuku, M. Ogata, Y. Iwakura,
S. Akira, T. Kitamura, A. Kosugi, M. Kimoto, and K. Miyake.
2002. Essential role of MD-1 in lipopolysaccharide responsiveness
and Toll-like receptor 4 distribution. Nat. Immunol.
||Miyake, K. Innate recognition of lipopolysaccharide by CD14
and toll-like receptor 4-MD-2: unique roles for MD-2. Int
Immunopharmacol. 2003 1:119-128
||S Akashi, S Saitoh, Y Wakabayashi, T Kikuchi, N Takamura,
Y Nagai, Y Kusumoto, K Fukase, S Kusumoto, Y Adachi, A Kosugi,
K Miyake. Lipopolysaccharide Interaction with Cell Surface
Toll-like Receptor 4-MD-2: Higher Affinity than that with
MD-2 or CD14. J. Exp. Med. 2003, 198: 1035-1042.
||Miyake K. Endotoxin recognition molecules, Toll-like receptor
4-MD-2. Semin Immunol. 2004 16:11-16.