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Tetsuro Matano, M.D., Ph.D.
Professor
International Research Center for Infectious Diseases
Institute of Medical Science
The University of Tokyo
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Education:
1979-1985 |
M.D. |
Faculty of Medicine, The University of Tokyo |
1990-1994 |
Ph.D. (D.M.Sc.) |
Graduate School of Medicine, The University of Tokyo |
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Professional Experience:
1985-1990 |
Orthopaedic Surgeon, Department of Orthopaedics,
Faculty of Medicine, The University of Tokyo |
1994-1995 |
Researcher, AIDS Research Center, National Institute of
Infectious Diseases |
1995-1997 |
Visiting Fellow, Laboratory of Molecular Microbiology, NIAID,
NIH |
1997-2001 |
Senior Researcher, AIDS Research Center, National Institute
of Infectious Diseases |
2001-2006 |
Associate Professor, Department of Microbiology, Graduate
School of Medicine, The University of Tokyo |
2006-Present |
Professor, International Research Center for Infectious
Diseases, Institute of Medical Science, The University of
Tokyo |
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Selected Publications
Matano, T., Shibata, R., Siemon, C., Connors, M., Lane,
H.C., and Martin, M.A. Administration of an anti-CD8 monoclonal
antibody interferes with the clearance of SIV/HIV chimeric virus
during primary infections of rhesus macaques. J. Virol. 72:164-169,
1998.
Matano, T., Kano, M., Nakamura, H., Takeda, A.,
and Nagai, Y. Rapid appearance of secondary immune responses and
protection from acute CD4 depletion after a highly pathogenic immunodeficiency
virus challenge in macaques vaccinated with a DNA-prime/Sendai viral
vector-boost regimen. J. Virol. 75:11891-11896, 2001.
Takeda, A., Igarashi, H., Nakamura, H., Kano, M., Iida,
A., Hirata, T., Hasegawa, M., Nagai, Y., and Matano, T.
Protective efficacy of an AIDS vaccine, a single DNA-prime followed
by a single booster with a recombinant replication-defective Sendai
virus vector, in a macaque AIDS model. J. Virol. 77:9710-9715, 2003.
Matano, T., Kobayashi, M., Igarashi, H., Takeda,
A., Nakamura, H., Kano, M., Sugimoto, C., Mori, K., Iida, A., Hirata,
T., Hasegawa, M., Yuasa, T., Miyazawa, M., Takahashi, Y., Yasunami,
M., Kimura, A., O'Connor, D.H., Watkins, D.I., and Nagai, Y. Cytotoxic
T lymphocyte-based control of simian immunodeficiency virus replication
in a preclinical AIDS vaccine trial. J. Exp. Med. 199:1709-1718,
2004.
Kobayashi, M., Igarashi, H., Takeda, A., Kato, M., and Matano,
T. Reversion in vivo after inoculation of a molecular proviral
DNA clone of simian immunodeficiency virus with a cytotoxic-T-lymphocyte
escape mutation. J. Virol. 79:11529-11532, 2005.
Kawada, M., Igarashi, H., Takeda, A., Tsukamoto, T., Yamamoto, H.,
Dohki, S., Takiguchi, M., and Matano, T. Involvement
of multiple epitope-specific cytotoxic T-lymphocyte responses in
vaccine-based control of simian immunodeficiency virus replication
in rhesus macaques. J. Virol. 80:1949-1958, 2006. |
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